Endocrine Abstracts

Aim: To assess lipid levels in patients with PCOS and BMI >25.Materials and methods: 102 patients admitted to the Gynaecologic Endocrinology Clinic of the Jagiellonian University’s Collegium Medicum agreed to take part in this research, and PCOS, according to the Rotterdam criteria, was found in 87 of them. The control group consisted of 15 patients with FAI <5. All of the 87 patients had BMI >25. This index, as well as blood samples, we...

Mutations in the (glucokinase) GCK gene are, along with the HNF1A gene mutations, the most frequent cause of (maturity onset diabetes of the young) MODY. Heterozygous loss-of-function GCK mutations result in a moderate fasting hyperglycemia. The GCK-MODY patients are usually free from microvascular complications; however, little is known about atherosclerosis and intermediate related phenotypes. We aimed to examine intima-media thickness (IMT) and endothelial function in GCK-M...

Severe thyroid disorder are associated with important metabolic changes. After restoration of euthyroidism, as a result of proper treatment, usually body metabolism also normalizes. Up to date, there are conflicting reports about the changes in body composition of patients during treatment of severe hyperthyroidism and hypothyroidism. The aim of this study was to evaluate the body composition and glucose level changes in subjects affected by Graves disease and autoimmune thyro...